从培养基中去除脂蛋白组分可纠正由AY9944诱导的酸性鞘磷脂酶活性降低。 - Suppr

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超能文献

Removal of lipoprotein fraction from culture media corrects the reduction of acid sphingomyelinase activity induced by AY9944.

作者信息

Yoshikawa H, Sakuragawa N

机构信息

Division of Inherited Metabolic Disorders, National Institute of Neuroscience, Tokyo, Japan.

出版信息

J Inherit Metab Dis. 1992;15(1):155-6. doi: 10.1007/BF01800359.

DOI:10.1007/BF01800359

PMID:1374822

Abstract

摘要

相似文献

Removal of lipoprotein fraction from culture media corrects the reduction of acid sphingomyelinase activity induced by AY9944.从培养基中去除脂蛋白组分可纠正由AY9944诱导的酸性鞘磷脂酶活性降低。

J Inherit Metab Dis. 1992;15(1):155-6. doi: 10.1007/BF01800359.

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[Experimental Niemann-Pick rat: additional studies on the specificity of the sphingomyelinase reduction in rats treated with AY 9944 (author's transl)].[实验性尼曼-皮克病大鼠：关于用AY 9944治疗的大鼠中鞘磷脂酶降低特异性的进一步研究（作者译）]

No To Shinkei. 1981 Jun;33(3):585-93.

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Calmodulin antagonists chlorpromazine and W-7 inhibit exogenous cholesterol esterification and sphingomyelinase activity in human skin fibroblast cultures. Similarities between drug-induced and Niemann-Pick type C lipidoses.

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Niemann-Pick disease: coupling and uncoupling of inhibited sphingomyelinase activity and exogenous cholesterol esterification in fibroblasts by ionophore treatment.

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Niemann-Pick type II fibroblasts exhibit impaired cholesterol esterification in response to sphingomyelin hydrolysis.II型尼曼-匹克病成纤维细胞在对鞘磷脂水解的反应中表现出胆固醇酯化受损。

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Intracellular transport of cholesterol in type C Niemann-Pick fibroblasts.C型尼曼-匹克成纤维细胞中胆固醇的细胞内运输

Biochim Biophys Acta. 1989 Oct 17;1005(3):303-9. doi: 10.1016/0005-2760(89)90053-2.

Reduction of acid sphingomyelinase activity in human fibroblasts induced by AY-9944 and other cationic amphiphilic drugs.AY - 9944及其他阳离子两亲性药物诱导人成纤维细胞中酸性鞘磷脂酶活性降低

J Biochem. 1985 Dec;98(6):1669-79. doi: 10.1093/oxfordjournals.jbchem.a135438.

Inhibition of sterol and DNA synthesis in peripheral blood lymphocytes by AY9944.

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本文引用的文献

Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol.胆固醇和7-脱氢胆固醇对人成纤维细胞鞘磷脂酶的抑制作用。

Biochem Biophys Res Commun. 1981 Jun 16;100(3):1299-304. doi: 10.1016/0006-291x(81)91965-3.

Correction of sphingomyelinase deficiency in Niemann-Pick type C fibroblasts by removal of lipoprotein fraction from culture media.通过去除培养基中的脂蛋白组分纠正尼曼-匹克C型成纤维细胞中的鞘磷脂酶缺乏症。

J Inherit Metab Dis. 1989;12(2):139-51. doi: 10.1007/BF01800716.

J Biochem. 1985 Dec;98(6):1669-79. doi: 10.1093/oxfordjournals.jbchem.a135438.

Effects of drugs on cholesterol esterification in normal and Niemann-Pick type C fibroblasts: AY-9944, other cationic amphiphilic drugs and DMSO.

Brain Dev. 1991;13(2):115-20. doi: 10.1016/s0387-7604(12)80118-5.

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