单个胎儿胰腺使大鼠实验性糖尿病完全逆转。
Complete reversal of experimental diabetes mellitus in rats by a single fetal pancreas.
作者信息
Mullen Y S, Clark W R, Molnar I G, Brown J
出版信息
Science. 1977 Jan 7;195(4273):68-70. doi: 10.1126/science.137524.
PMID:137524
Abstract
Complete reversal of streptozotocin-induced diabetes mellitus in adult rats will follow transplantation of a single fetal pancreas if the organ is first grown in a normal syngeneic carrier before transfer to the diabetic recipient. Careful control of the blood sugar of diabetic recipients may enhance the function of a single donor organ and thus improve histocompatibility matching.
摘要
如果将单个胎儿胰腺先在正常同基因载体中培养，然后再移植给成年糖尿病大鼠受体，链脲佐菌素诱导的糖尿病成年大鼠的糖尿病状态将完全逆转。仔细控制糖尿病受体的血糖可能会增强单个供体器官的功能，从而改善组织相容性匹配。
Zotero 插件