Schmitt-Gräff A, Borchard F
Department of Pathology, University Medical Center, Geneva, Switzerland.
Pathol Res Pract. 1992 Feb;188(1-2):217-21; discussion 221-5. doi: 10.1016/S0344-0338(11)81184-2.
This study documents the expression of cytokeratin intermediate filaments (IFs) in a surgically excised glandular atrial myxoma. The glandular structures showed also positivity for carcinoembryonic antigen. Typical isolated or cordlike myxoma cells contained vimentin IFs. Positivity for von Willebrand factor was detected in cells lining deep invaginations of surface papillae and vascular channels. Bundles of smooth muscle cells and myofibroblasts scattered throughout the myxoid matrix synthesized the isoform of alpha-actin specific for smooth muscle.
本研究记录了细胞角蛋白中间丝（IFs）在手术切除的腺性心房黏液瘤中的表达情况。腺性结构对癌胚抗原也呈阳性反应。典型的孤立或条索状黏液瘤细胞含有波形蛋白中间丝。在表面乳头和血管通道深部凹陷内衬的细胞中检测到血管性血友病因子呈阳性。散在于黏液样基质中的平滑肌细胞和成肌纤维细胞束合成了平滑肌特异性的α-肌动蛋白异构体。
