Reilly J A, Hallett M, Cohen L G, Tarkka I M, Dang N
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Electroencephalogr Clin Neurophysiol. 1992 May-Jun;84(3):243-7. doi: 10.1016/0168-5597(92)90005-v.
We recorded short-latency median nerve somatosensory evoked potentials (SEPs) in 10 patients with dystonia (6 with focal dystonia, 3 with generalized dystonia, and 1 with segmental dystonia) and compared them with those of 10 normal controls. The EEG was recorded from 29 sites on the scalp with linked earlobe electrodes for reference. Latencies and amplitudes of P15, postcentral N20 and P45, and frontal N30 were evaluated. The latencies of all potentials were the same in patients and controls. The amplitudes of P15, N20 and P45 were also the same in both groups, but the N30 amplitude of the patients was larger than of the controls. The amplitude of N30 did not vary from the affected side to the unaffected side. Previous work has shown decreased N30 amplitude in patients with Parkinson's disease. Changes in N30 amplitude may be indicative of abnormal excitatory effects on cortex resulting from disorders of the basal ganglia.
我们记录了10例肌张力障碍患者（6例局灶性肌张力障碍、3例全身性肌张力障碍和1例节段性肌张力障碍）的短潜伏期正中神经体感诱发电位（SEP），并将其与10名正常对照者的进行比较。脑电图通过连接耳垂电极作为参考，从头皮上的29个部位进行记录。评估了P15、中央后回N20和P45以及额叶N30的潜伏期和波幅。患者和对照者所有电位的潜伏期相同。两组中P15、N20和P45的波幅也相同，但患者的N30波幅大于对照者。N30波幅在患侧和未患侧之间没有差异。先前的研究表明帕金森病患者的N30波幅降低。N30波幅的变化可能表明基底神经节疾病对皮质产生了异常兴奋作用。
