Jancsó G, Tóth L, Karcsú S
Z Mikrosk Anat Forsch. 1975;89(6):983-90.
Since the regulation of the vascular permeability in the CNS is dependent partly on the enzymes associated with the wall of brain capillaries, the histochemical demonstration of these enzymes may furnish further data on the function of the blood brain barrier (BBB), a new methodological approach, using brain smears was developed for the histochemical demonstration of several enzymes participating in the function of the BBB. The method presented renders possible also the subsequent demonstration of monoamines and the activity of different enzymes in the same tissue preparation. The usefulness of this simple technique in the study of brain capillary functions is discussed.
由于中枢神经系统中血管通透性的调节部分取决于与脑毛细血管壁相关的酶，这些酶的组织化学显示可能会提供有关血脑屏障（BBB）功能的更多数据。为此开发了一种新的方法，即使用脑涂片进行组织化学显示参与血脑屏障功能的几种酶。所提出的方法还可以在同一组织标本中随后显示单胺和不同酶的活性。本文讨论了这种简单技术在研究脑毛细血管功能中的实用性。
