Ciani F, Franceschini V
J Hirnforsch. 1984;25(1):11-20.
We have investigated the ultrastructural and histochemical (AChE and BuChE) features of intracerebral vessels in newt. The blood vessels of the newt brain are paired and end in a closed loop. The two limbs, each of them has delineate the lumen by one endothelial cell, are enclosed within a single basement membrane and are separated from each other by a thin intercapillary wall. The brain capillaries are un-fenestrated and the overlapping endothelial cells were connected by clefts. Ependymal astrocytes extensively ensheath the surface of brain capillaries, but the sheats are incomplete. Pericytes and mast cells are frequently sandwiched in the endothelial basal lamina. Microglial cells are also present adjacent to cerebral vessels. The newt cerebral capillaries are characterized by high levels of AChE. This enzyme is localized in the basal membrane and in extracellular spaces between the overlapping endothelial cells. The vascular walls are instead deprived of BuChE activity. The non-nervous role of cholinesterases is discussed.
我们研究了蝾螈脑内血管的超微结构和组织化学（乙酰胆碱酯酶和丁酰胆碱酯酶）特征。蝾螈脑的血管是成对的，并终止于一个闭环。这两条血管分支，每条都由一个内皮细胞界定管腔，被包裹在一层共同的基底膜内，并由一层薄的毛细血管间壁彼此分隔。脑毛细血管无窗孔，重叠的内皮细胞通过缝隙相连。室管膜星形胶质细胞广泛地包裹着脑毛细血管的表面，但包被并不完整。周细胞和肥大细胞经常夹在在内皮基底膜中。小胶质细胞也存在于脑血管附近。蝾螈脑毛细血管的特征是乙酰胆碱酯酶水平较高。这种酶定位于基底膜以及重叠内皮细胞之间的细胞外间隙。相反，血管壁缺乏丁酰胆碱酯酶活性。本文讨论了胆碱酯酶的非神经作用。
