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The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation.

作者信息

Tabcharani J A, Chang X B, Riordan J R, Hanrahan J W

机构信息

Department of Physiology, McGill University, Montréal, Québec, Canada.

出版信息

Biophys J. 1992 Apr;62(1):1-4. doi: 10.1016/S0006-3495(92)81759-9.

DOI:10.1016/S0006-3495(92)81759-9
PMID:1376160
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1260465/
Abstract
摘要

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The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation.囊性纤维化跨膜传导调节因子氯离子通道。碘离子阻断与通透。
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2
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells.囊性纤维化跨膜传导调节因子的表达可纠正囊性纤维化气道上皮细胞中缺陷性氯离子通道调节。
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3
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Noise analysis and single-channel observations of 4 pS chloride channels in human airway epithelia.人气道上皮细胞中4 pS氯离子通道的噪声分析与单通道观察
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Towards the biochemical defect in cystic fibrosis.关于囊性纤维化的生化缺陷
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本文引用的文献

1
Identification of the cystic fibrosis gene: chromosome walking and jumping.囊性纤维化基因的鉴定：染色体步移与跳跃
Science. 1989 Sep 8;245(4922):1059-65. doi: 10.1126/science.2772657.
2
Cl- conductance and acid secretion in the human sweat duct.人汗腺导管中的氯离子电导与酸分泌
Ann N Y Acad Sci. 1989;574:438-46. doi: 10.1111/j.1749-6632.1989.tb25182.x.
3
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.囊性纤维化基因的鉴定：互补DNA的克隆与特性分析
Science. 1989 Sep 8;245(4922):1066-73. doi: 10.1126/science.2475911.
4
Two types of chloride channel on duct cells cultured from human fetal pancreas.从人胎儿胰腺培养的导管细胞上的两种氯离子通道。
Am J Physiol. 1989 Aug;257(2 Pt 1):C240-51. doi: 10.1152/ajpcell.1989.257.2.C240.
5
Cystic fibrosis: a disease in electrolyte transport.囊性纤维化：一种电解质转运疾病。
FASEB J. 1990 Jul;4(10):2709-17. doi: 10.1096/fasebj.4.10.2197151.
6
Separate Cl- conductances activated by cAMP and Ca2+ in Cl(-)-secreting epithelial cells.氯离子分泌上皮细胞中由环磷酸腺苷（cAMP）和钙离子（Ca2+）激活的不同氯离子电导。
Proc Natl Acad Sci U S A. 1990 Jul;87(13):4956-60. doi: 10.1073/pnas.87.13.4956.
7
Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.表达囊性纤维化基因的非洲爪蟾卵母细胞中的氯离子通道活性。
J Biol Chem. 1991 Oct 15;266(29):19142-5.
8
Phosphorylation-regulated Cl- channel in CHO cells stably expressing the cystic fibrosis gene.在稳定表达囊性纤维化基因的CHO细胞中受磷酸化调节的氯离子通道
Nature. 1991 Aug 15;352(6336):628-31. doi: 10.1038/352628a0.
9
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity.通过改变其阴离子选择性来证明囊性纤维化跨膜传导调节因子是一种氯离子通道。
Science. 1991 Jul 12;253(5016):202-5. doi: 10.1126/science.1712984.
10
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance.囊性纤维化基因在非上皮无脊椎动物细胞中的表达产生了一种受调控的阴离子电导。
Cell. 1991 Feb 22;64(4):681-91. doi: 10.1016/0092-8674(91)90498-n.