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Comparison of hematopoietic and immune recovery after autologous bone marrow or blood stem cell transplants.

作者信息

Henon P R, Liang H, Beck-Wirth G, Eisenmann J C, Lepers M, Wunder E, Kandel G

机构信息

Service d'Hématologie, Hopital du Hasenrain, Mulhouse, France.

出版信息

Bone Marrow Transplant. 1992 Apr;9(4):285-91.

PMID:1376185
Abstract

We studied hematopoietic and immune recovery in 40 subjects receiving autologous bone marrow (ABMT) or blood stem cell transplants (ABSCT). Supportive care, transplant-related morbidity, duration of hospitalization and cost were also considered. ABSCT was associated with more rapid recovery of all hematopoietic lineages than was ABMT. However, kinetics of immune recovery were similar between the groups. In the ABSCT group, there was a correlation between numbers of blood progenitor cells infused and the rate of hematopoietic recovery. The accelerated hematopoietic recovery following ABSCT correlated with less morbidity, fewer transfusions, briefer hospitalization and lower cost than ABMT.

摘要

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