Hoffmann A
Innere Medizin FMH, spez. Herzkrankheiten, Basel.
Schweiz Med Wochenschr. 1992 May 23;122(21):821-5.
The primary care physician should be cautious and restrictive in the treatment of cardiac arrhythmias and adhere to the well established modalities only. For supraventricular arrhythmias digitalis, verapamil, quinidine and betablocking agents are the drugs of choice. In atrial fibrillation oral anticoagulants and in some cases aspirin seem to be beneficial for the prevention of stroke in selected subgroups of patients. Criteria for their use are outlined in Tables 1 and 2. Ventricular arrhythmias in healthy persons generally should not be treated. In patients with coronary artery disease and severely compromised left ventricular function amiodarone is very effective for the treatment of complex ventricular arrhythmias. If other antiarrhythmics are to be used, the advice of a cardiologist is strongly recommended, as proarrhythmic effects are particularly common in severe cardiac conditions. Severely symptomatic patients with recurrent ventricular tachycardia and syncope should be offered invasive evaluation in order to determine effective medical or surgical treatment.
基层医疗医生在治疗心律失常时应谨慎且有所限制,仅采用已确立的治疗方法。对于室上性心律失常,洋地黄、维拉帕米、奎尼丁和β受体阻滞剂是首选药物。在房颤患者中,口服抗凝剂以及在某些情况下阿司匹林似乎对特定亚组患者预防中风有益。其使用标准在表1和表2中列出。健康人中的室性心律失常一般不应治疗。在患有冠状动脉疾病且左心室功能严重受损的患者中,胺碘酮对治疗复杂性室性心律失常非常有效。如果要使用其他抗心律失常药物,强烈建议咨询心脏病专家,因为促心律失常作用在严重心脏疾病中尤为常见。有严重症状的复发性室性心动过速和晕厥患者应接受侵入性评估,以确定有效的药物或手术治疗方案。