Tsinzerling A V, Ioakimova N V, Shastina G V, Tsinzerling V A, Piskareva N A
Arkh Patol. 1976;38(11):60-6.
A total of 50 section cases of meningitis in children were investigated. All patients revealed acute viral respiratory infections with generalization, including lesions of the central nervous system (CNS). In 14 children moreover meningococcal infection was diagnosed. In 30 children lesions of the CNS were due to mixed bacterial microflora. In 6 children along with acute viral respiratory infections (AVRI) mycoplasmosis was also revealed. Etiology of the process was determined on the basis of characteristic structural changes in the CNS and other organs, findings of virological and bacteriological investigations. In the majority of children the intravascular blood coagulation was observed. Waterhouse-Friderichsen's syndrome was revealed mainly in meningococcal infection. In order to ascertain the data obtained case records of 120 children, who had undergone treatment in connection with meningococcal infection, were analysed. It turned out that all 42 children, who had developed this disease independently, recovered. Combination of the disease with AVRI led to fatal outcomes in 12 cases out of 72.
共对50例儿童脑膜炎病例进行了调查。所有患者均表现为急性病毒性呼吸道感染并伴有全身症状,包括中枢神经系统(CNS)病变。此外,14名儿童被诊断为脑膜炎球菌感染。30名儿童的中枢神经系统病变是由混合细菌菌群引起的。6名儿童除急性病毒性呼吸道感染(AVRI)外,还发现有支原体感染。根据中枢神经系统和其他器官的特征性结构变化、病毒学和细菌学检查结果确定了病程的病因。大多数儿童观察到血管内凝血。华-弗综合征主要在脑膜炎球菌感染中出现。为了确定所获得的数据,分析了120名因脑膜炎球菌感染接受治疗的儿童的病例记录。结果发现,42名独立患此病的儿童全部康复。该疾病与急性病毒性呼吸道感染合并,在72例中有12例导致了致命后果。