Dash Nihar, Ameen Abdulmajeed S, Sheek-Hussein Mohamud M, Smego Raymond A
Department of Control of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Int J Infect Dis. 2007 Jul;11(4):309-12. doi: 10.1016/j.ijid.2006.05.009. Epub 2006 Sep 6.
To describe the epidemiologic features of meningitis in Al-Ain Medical District, United Arab Emirates from January 2000 through June 2005.
A retrospective review of clinical records and notification forms for cases of meningitis reported to the Department of Preventive Medicine, Al-Ain. Data collected and compiled included demographic features, causative microbiologic agents, and annual incidence rates of meningitis, by etiology.
Ninety-two cases of meningitis were reported during the study period; 53% were bacterial and 37% were viral in origin. Neisseria meningitidis was the leading bacterial pathogen (35%) followed by Streptococcus pneumoniae (16%). Ten percent of clinically diagnosed cases of meningitis had no causative microorganism recovered, and in 33% of patients with presumed pyogenic meningitis no specific bacterial pathogen could be identified. The peak occurrence of meningitis was in young children less than one year old. Most cases of meningococcal meningitis were seen among prison inmates and laborers, while viral meningitis occurred mainly in children and young adults attending school. The incidence rate of meningitis in Al-Ain ranged between 2.2/100,000 population in 2000 and 1/100,000 in 2005, with an overall downward trend by year. The incidence of Haemophilus influenzae type b decreased significantly after implementation of the national immunization program in 1999.
Improved methods of bacterial detection including isolate serotyping must be made available in order to further reduce mortality and morbidity from meningitis.
描述2000年1月至2005年6月阿联酋艾因医疗区脑膜炎的流行病学特征。
对向艾因预防医学部报告的脑膜炎病例的临床记录和通报表进行回顾性审查。收集和汇编的数据包括人口统计学特征、致病微生物病原体以及按病因分类的脑膜炎年发病率。
研究期间报告了92例脑膜炎病例;53%为细菌性,37%为病毒性。脑膜炎奈瑟菌是主要的细菌病原体(35%),其次是肺炎链球菌(16%)。10%临床诊断的脑膜炎病例未分离出致病微生物,33%疑似化脓性脑膜炎患者未鉴定出特定细菌病原体。脑膜炎发病高峰出现在1岁以下幼儿中。大多数脑膜炎球菌性脑膜炎病例见于囚犯和劳工,而病毒性脑膜炎主要发生在上学的儿童和年轻人中。艾因的脑膜炎发病率在2000年为2.2/10万人口,2005年为1/10万,总体呈逐年下降趋势。1999年实施国家免疫规划后,b型流感嗜血杆菌的发病率显著下降。
必须提供改进的细菌检测方法,包括分离株血清分型,以进一步降低脑膜炎的死亡率和发病率。