Annerén G, Nordlinder H, Hedborg F
Department of Clinical Genetics, University Hospital, Uppsala, Sweden.
Genes Chromosomes Cancer. 1992 Jan;4(1):99-100. doi: 10.1002/gcc.2870040117.
The cytogenetic findings of an alpha-fetoprotein (AFP)-producing hepatoblastoma in a 14-month-old girl are reported. Ten of 36 tumor cells were chromosomally abnormal, yielding the composite karyotype 47,XX,2q +, t(3;5)(p25;q31),dup(4)(q12q26), +20. Three of the chromosomal abnormalities (2q+, break at 4q12, +20) have been reported previously and might be of pathogenetic significance.
