Swarts S, Wisecarver J, Bridge J A
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198-5440, USA.
Cancer Genet Cytogenet. 1996 Oct 1;91(1):65-7. doi: 10.1016/s0165-4608(96)00128-8.
Cytogenetic analysis of both primary and metastatic hepatoblastoma revealed the following abnormal chromosomal complements respectively: 46,XX,der(2)t(2;2)(p25;q21),der(22)t(1;22)(q22;p13) [6]/47,XX,der(2)t(2;2)(p25;q21),+20,der(22)t(1;22)q22;p13)[4]/47,XX,der (2)t(2;2)(p25;q21), +20[1], and 48,XX,der(2)t(2;2)(p25;q21),+12,+17, -18,+20,der(22)t(1;22)(q22;p13)[9]/50,XX,der(2)t(2;2)(p25;q21), +8,+12,+17,+20[4]. Two abnormalities, the chromosome 2 derivative and trisomy 20, are recurrent in hepatoblastoma, but the derivative involving chromosomes 1 and 22 is a novel abnormality.
