Lui H, Stewart W D, English J C, Wood W S
Division of Dermatology, University of British Columbia, Vancouver, Canada.
J Am Acad Dermatol. 1992 May;26(5 Pt 2):805-13. doi: 10.1016/0190-9622(92)70110-2.
A 56-year-old man had an 11-year history of a psoriasiform eruption of the palms, soles, and shins. An examination revealed well-demarcated patches and plaques of erythematous, fissured, and hyperkeratotic skin with focal erosions. There was no clinical evidence of ectodermal dysplasia. On histologic examination these lesions proved to be eccrine hamartomas that consisted of anastomosing cords and strands of cuboidal epithelial cells with well-formed ducts and a fibrovascular mucinous stroma. Eccrine ductal origin was indicated by histopathologic, histochemical, immunopathologic, and electron microscopic evaluation. These multiple palmoplantar eccrine hamartomas, unassociated with ectodermal dysplasia, represent a sporadic hamartomatous condition that is best designated as "eccrine syringofibroadenomatosis."
一名56岁男性有手掌、足底和小腿部银屑病样皮疹11年病史。检查发现有边界清楚的红斑、裂隙和角化过度皮肤斑块及斑片，伴有局灶性糜烂。无外胚层发育不良的临床证据。组织学检查显示这些病变为小汗腺错构瘤，由相互吻合的立方形上皮细胞索和束组成，有发育良好的导管及含纤维血管的黏液性间质。组织病理学、组织化学、免疫病理学及电子显微镜评估均表明病变起源于小汗腺导管。这些多发的掌跖部小汗腺错构瘤与外胚层发育不良无关，代表一种散发性错构瘤病，最好命名为“小汗腺汗管纤维腺瘤病”。
