地塞米松对神经生长因子诱导的PC12细胞中尼罗糖蛋白增加的影响。
Effect of dexamethasone on the nerve growth factor-induced increase in the NILE glycoprotein in PC12 cells.
作者信息
Tocco M D, Fujita K, Guroff G
机构信息
Section of Growth Factors, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892.
出版信息
J Neurosci Res. 1992 Jan;31(1):28-32. doi: 10.1002/jnr.490310105.
PMID:1377284
Abstract
The long-known and well-documented increase in the NILE glycoprotein produced by nerve growth factor in PC12 cells is prevented by simultaneous treatment with dexamethasone. The absence of this surface marker on the fully differentiated cells has been demonstrated by both glucosamine incorporation and immunohistofluorescence.
摘要
神经生长因子在PC12细胞中产生的尼罗糖蛋白的长期已知且有充分记录的增加，可通过同时用地塞米松处理来阻止。通过氨基葡萄糖掺入和免疫荧光法已证明完全分化的细胞上不存在这种表面标志物。
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