Gidron E, Margalit R, Oliven A, Shalitin Y
Br Heart J. 1977 Jan;39(1):19-24. doi: 10.1136/hrt.39.1.19.
A systematic investigation of the fibrinolytic system during the period after acute myocardial infarction in 42 patients showed a progressive reduction of fibrinolytic activity, with the longest lysis times on days 4 to 5 after the event. There is a concomitant rise in the levels of fibrinogen, plasminogen, and antiplasmin; only the latter parallels the delay in lysis. After 12 to 15 months, normal lysis times and fibrinogen levels were found in 24 patients re-examined. It is concluded that the reduced fibrinolytic activity in these patients was a transient phenomenon after myocardial infarction.
对42例急性心肌梗死后患者纤溶系统的系统性研究显示,纤溶活性呈进行性降低,在发病后第4至5天的溶解时间最长。纤维蛋白原、纤溶酶原和抗纤溶酶水平随之升高;只有后者与溶解延迟情况平行。12至15个月后,对24例重新检查的患者发现其溶解时间和纤维蛋白原水平正常。得出的结论是,这些患者纤溶活性降低是心肌梗死后的一种短暂现象。