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1
A rapid screening test for reduced fibrinolytic activity of plasma: streptokinase activated lysis time.血浆纤维蛋白溶解活性降低的快速筛查试验:链激酶激活溶解时间
J Clin Pathol. 1978 Jan;31(1):54-7. doi: 10.1136/jcp.31.1.54.
2
The influence of various combinations of plasminogen and streptokinase on fibrinolysis.纤溶酶原与链激酶的不同组合对纤维蛋白溶解的影响。
Haemostasis. 1981;10(6):304-14. doi: 10.1159/000214416.
3
Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay.使用优球蛋白溶解试验和纤溶酶原激活试验对五种链激酶制剂进行分析。
Braz J Med Biol Res. 2004 Dec;37(12):1889-94. doi: 10.1590/s0100-879x2004001200015. Epub 2004 Nov 17.
4
In vitro comparison of fibrinolytic activity of plasminogen activators using a thrombelastographic method: in vivo evaluation of the B-chain-streptokinase complex in the dog model using pre-titered doses.使用血栓弹力图法对纤溶酶原激活剂的纤溶活性进行体外比较:在犬模型中使用预滴定剂量对B链-链激酶复合物进行体内评估。
Thromb Haemost. 1986 Aug 20;56(1):71-9.
5
Assessment of fibrinolytic activity by measuring the lysis time of a tissue-factor-induced clot: a feasibility evaluation.通过测量组织因子诱导的凝块的溶解时间来评估纤维蛋白溶解活性:可行性评估。
Clin Appl Thromb Hemost. 2010 Jun;16(3):337-44. doi: 10.1177/1076029608325542. Epub 2008 Dec 30.
6
The evaluation of plasmin and streptokinase activator complexes in a new rabbit model of venous thrombosis.在一种新的兔静脉血栓形成模型中对纤溶酶和链激酶激活剂复合物的评估。
Thromb Haemost. 1981 Aug 28;46(2):528-34.
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A comparison of acylated streptokinase-plasminogen complex and streptokinase in healthy volunteers.健康志愿者中酰化链激酶-纤溶酶原复合物与链激酶的比较。
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8
A method for the measurement of fibrinolytic activity based on one dimensional diffusion using small glass tubes. II. With special reference to the differences between the use of plasminogen-rich fibrinogen and that of plasminogen-free fibrinogen as the substrates.一种基于使用小玻璃管进行一维扩散来测量纤溶活性的方法。II. 特别提及以富含纤溶酶原的纤维蛋白原和不含纤溶酶原的纤维蛋白原作为底物时的差异。
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9
Evidence for a sustained fibrinolytic response to anisoylated plasminogen streptokinase activator complex in vitro.体外对茴香酰化纤溶酶原链激酶激活剂复合物持续纤溶反应的证据。
Drugs. 1987;33 Suppl 3:83-7. doi: 10.2165/00003495-198700333-00012.
10
Clot lysis in a perfusion system.
Thromb Diath Haemorrh. 1966 Jan 31;15(1):205-19.

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1
Microbial Fibrinolytic Enzymes as Anti-Thrombotics: Production, Characterisation and Prodigious Biopharmaceutical Applications.作为抗血栓药物的微生物纤溶酶:生产、表征及巨大的生物制药应用
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2
Development and Testing of Thrombolytics in Stroke.溶栓药物在中风治疗中的研发与测试。
J Stroke. 2021 Jan;23(1):12-36. doi: 10.5853/jos.2020.03349. Epub 2021 Jan 31.
3
Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study.使用凝血块溶解时间和活化部分凝血活酶时间(APTT)溶解方法测定重组瑞替普酶的生物活性:一项比较研究。
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本文引用的文献

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In-vitro and in-vivo studies of a preparation of urokinase.尿激酶制剂的体外和体内研究。
Br Med J. 1963 Apr 6;1(5335):909-15. doi: 10.1136/bmj.1.5335.909.
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Simple syneresis procedure for fibrinogen assay.用于纤维蛋白原测定的简易脱水收缩程序。
Scand J Clin Lab Invest. 1961;13:530.
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Methods for the evaluation of human fibrinolysis; studies with two combined technics.人类纤维蛋白溶解评估方法;两种联合技术的研究
Am J Clin Pathol. 1958 Feb;29(2):104-12. doi: 10.1093/ajcp/29.2.104.
4
Evidence of a diurnal fibrinolytic rhythm; with a simple method of measuring natural fibrinolysis.昼夜纤维蛋白溶解节律的证据;采用一种测量自然纤维蛋白溶解的简单方法。
Clin Sci. 1957 Nov;16(4):645-50.
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Bile acid content of human serum. I. Serum bile acids in patients with hepatic disease.人血清中的胆汁酸含量。I. 肝病患者的血清胆汁酸
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The fibrin plate method for estimating fibrinolytic activity.用于评估纤维蛋白溶解活性的纤维蛋白平板法。
Arch Biochem Biophys. 1952 Oct;40(2):346-51. doi: 10.1016/0003-9861(52)90121-5.
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Conjugated and unconjugated serum bile acid levels n patients with hepatobiliary diseases.肝胆疾病患者血清结合及非结合胆汁酸水平
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8
A new technique for the quantitative estimation of fibrinolysis using in vitro (125-I)fibrinogen.一种使用体外(125-I)纤维蛋白原定量评估纤维蛋白溶解的新技术。
Br J Haematol. 1971 Jun;20(6):611-21. doi: 10.1111/j.1365-2141.1971.tb00799.x.
9
Dynamics of the enterohepatic circulation of bile acids. Postprandial serum concentrations of conjugates of cholic acid in health, cholecystectomized patients, and patients with bile acid malabsorption.胆汁酸的肠肝循环动力学。健康人、胆囊切除患者及胆汁酸吸收不良患者餐后血清中胆酸共轭物的浓度。
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10
Postprandial serum bile acid for the detection of hepatobiliary disease.餐后血清胆汁酸用于肝胆疾病的检测。
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血浆纤维蛋白溶解活性降低的快速筛查试验:链激酶激活溶解时间

A rapid screening test for reduced fibrinolytic activity of plasma: streptokinase activated lysis time.

作者信息

Gidron E, Margalit R, Shalitin Y

出版信息

J Clin Pathol. 1978 Jan;31(1):54-7. doi: 10.1136/jcp.31.1.54.

DOI:10.1136/jcp.31.1.54
PMID:627618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476720/
Abstract

A simple screening method for determining the fibrinolytic activity of plasma is described. A streptokinase activated system is used, which measures the result of the interplay of all components of the fibrinolytic system with the exception of activators, which are added in excess. Mean lysis time and standard deviation with this method is 6.9 +/- 1.4 min. The sensitivity of the method in detecting minor delays in clot lysis time is demonstrated.

摘要

本文描述了一种用于测定血浆纤溶活性的简单筛选方法。使用链激酶激活系统,该系统测量纤溶系统所有成分相互作用的结果,但不包括过量添加的激活剂。用这种方法测得的平均溶解时间和标准差为6.9±1.4分钟。证明了该方法在检测凝血块溶解时间微小延迟方面的敏感性。