Ohdo S, Sonoda T, Ohba K, Hayakawa K
Department of Pediatrics, Miyazaki Medical College, Japan.
Acta Paediatr Jpn. 1992 Apr;34(2):144-50. doi: 10.1111/j.1442-200x.1992.tb00941.x.
Etiology and pathogenesis of MCA/MR in 1,023 patients (618 male; 405 female) with mental retardation were studied. Of 1,023 patients, there were 563 cases (317 male; 246 female) with MCA (55%). Among the MCA patients, there were 303 (156 male; 147 female) whose primary etiology was clarified (53.8%). Among the 260 patients with MCA/MR of unknown etiology, there were 23 with recognizable syndromes of unknown etiology and 7 previously reported by us as possibly having a new malformation syndrome. We had 569 patients with mental retardation of unknown etiology including 263 (41.5%) who were involved with MCA.
对1023例智力发育迟缓患者（618例男性；405例女性）的脑性瘫痪/智力障碍（MCA/MR）的病因及发病机制进行了研究。在1023例患者中，有563例（317例男性；246例女性）患有脑性瘫痪（55%）。在脑性瘫痪患者中，有303例（156例男性；147例女性）的主要病因已明确（53.8%）。在260例病因不明的脑性瘫痪/智力障碍患者中，有23例具有病因不明的可识别综合征，还有7例我们之前报道过可能患有新的畸形综合征。我们有569例病因不明的智力发育迟缓患者，其中263例（41.5%）与脑性瘫痪有关。
