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对4500名发育迟缓个体的临床评估。

Clinical assessment of 4500 developmentally delayed individuals.

作者信息

Einfeld S L

出版信息

J Ment Defic Res. 1984 Jun;28 ( Pt 2):129-42. doi: 10.1111/j.1365-2788.1984.tb01004.x.

DOI:10.1111/j.1365-2788.1984.tb01004.x
PMID:6205153
Abstract

Data collected on 4500 developmentally delayed clients and classified according to a modification of Heber's criteria are presented. Statistically significant associations between variables are described. Although such associations are not necessarily biologically meaningful on this evidence alone, they are presented for comparison with other data collections and to suggest areas of further investigation. An examination is made of data relating to mental retardation of unknown cause compared with mental retardation of known causes. The unknown group most resembles those with metabolic disease and least resembles those with chromosome aneuploidy. The data also suggest that mental retardation secondary to brain injury is uncommonly associated with evidence of genetic predisposition.

摘要

本文呈现了收集到的4500名发育迟缓患者的数据,并根据对赫伯标准的修订进行了分类。描述了变量之间具有统计学意义的关联。尽管仅凭这些证据这些关联不一定具有生物学意义,但呈现这些关联是为了与其他数据收集结果进行比较,并指出进一步研究的领域。对与不明原因智力迟钝相关的数据和已知原因智力迟钝相关的数据进行了检查。不明原因组与代谢疾病患者最为相似,与染色体非整倍体患者最不相似。数据还表明,脑损伤继发的智力迟钝与遗传易感性证据的关联并不常见。

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引用本文的文献

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Genetic basis of cognitive disability.认知障碍的遗传基础。
Dialogues Clin Neurosci. 2001 Mar;3(1):37-46. doi: 10.31887/DCNS.2001.3.1/jflint.
2
Investigation of children with "developmental delay".对患有“发育迟缓”的儿童进行调查。
West J Med. 2002 Jan;176(1):29-33. doi: 10.1136/ewjm.176.1.29.
3
Pregnancy and birth risk factors for intellectual disability in South Australia.
Eur J Epidemiol. 1989 Sep;5(3):322-7. doi: 10.1007/BF00144832.
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Chromosome abnormalities in pupils attending ESN/M schools.就读于特殊需求教育/融合教育学校的学生的染色体异常。
Arch Dis Child. 1986 Mar;61(3):223-6. doi: 10.1136/adc.61.3.223.