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[高海拔条件下大鼠心脏乳头肌的机械活动]

[Mechanical activity of the papillary muscles of the rat heart under high altitude conditions].

作者信息

Daniiarov S B, Karasaeva A Kh, Naumova T N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1976;62(6):906-11.

PMID:137822
Abstract

Mechanical activity of isolated papillary muscles in the left ventricle of rats was studied during permanent high altitude adaptation. The main computer parameters were: maximal developing tension, force of contraction, and capacity of papillary muscles at different periods of mountain adaptation (3, 15, 30 and 45 days). On the 15th day of mountain exposure, a statistically significant increase of maximal developing tension and papillary muscles activity was observed, which remained until the 45th day. Capacity was considerably increased on the 30th--45th day of adaptation. The data suggest positive effect of high altitude hypoxia on inotropic function of intact myocardium.

摘要

在长期高原适应过程中,对大鼠左心室分离乳头肌的机械活动进行了研究。主要计算机参数包括:在高原适应的不同时期(3天、15天、30天和45天)的最大发展张力、收缩力和乳头肌能力。在高原暴露的第15天,观察到最大发展张力和乳头肌活动有统计学意义的增加,这种增加一直持续到第45天。在适应的第30 - 45天,能力显著增加。数据表明高原低氧对完整心肌的变力功能有积极影响。

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