WEATHERALL J A
Br J Pharmacol Chemother. 1960 Sep;15(3):454-7. doi: 10.1111/j.1476-5381.1960.tb01272.x.
Pentobarbitone was more toxic to new-born than to adult rabbits and rats, produced a longer loss of righting reflex in new-born animals but did not anaesthetize them effectively in less than toxic doses. Urethane did not anaesthetize new-born animals in doses which anaesthetized adults. Ether produced loss of righting reflex at lower concentrations for new-born than for adults, but the new-born animals became anaesthetized more slowly.
戊巴比妥对新生兔和大鼠的毒性比对成年兔和大鼠的毒性更大，使新生动物的翻正反射消失时间更长，但在低于中毒剂量时不能有效地麻醉它们。氨基甲酸乙酯在能麻醉成年动物的剂量下不能麻醉新生动物。乙醚使新生动物翻正反射消失的浓度低于成年动物，但新生动物麻醉得更慢。
