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[终末期癌症的持续药物输注]

[Continuous drug infusion in terminal cancer].

作者信息

Ottesen S, Manger A T, Monrad L

机构信息

Anestesiavdelingen, Baerum sykehus.

出版信息

Tidsskr Nor Laegeforen. 1992 May 30;112(14):1836-9.

PMID:1378657
Abstract

Today's technology provides portable pumps which facilitate continuous infusion of drugs to relieve suffering in terminal disease. Subcutaneous and epidural infusion is now frequently used in our hospital. The most common indications are gastrointestinal obstruction, impaired absorption of drugs, refractory side effects of oral medication or poor compliance because good pain relief is no longer possible orally. During the last days of life, this method may be the only possible approach to good comfort and relief from terminal agitation and anxiety. Of the patients referred to the advisory group for seriously ill and dying in 1990, 64% received subcutaneous infusions and 15% epidural infusions during the last days or weeks of life. Continuous infusion of drugs from portable pumps has become an almost indispensible method of treatment in an ordinary clinic.

摘要

如今的技术提供了便携式泵,便于持续输注药物以减轻绝症患者的痛苦。皮下和硬膜外输注目前在我院经常使用。最常见的适应证是胃肠道梗阻、药物吸收受损、口服药物的难治性副作用或依从性差,因为口服已无法实现良好的疼痛缓解。在生命的最后几天,这种方法可能是实现良好舒适度以及缓解临终躁动和焦虑的唯一可行途径。在1990年被转诊至重病和临终咨询小组的患者中,64%在生命的最后几天或几周接受了皮下输注,15%接受了硬膜外输注。通过便携式泵持续输注药物已成为普通诊所几乎不可或缺的治疗方法。

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