Opelz G, Glovsky M M
J Immunogenet. 1976 Oct;3(5):303-6. doi: 10.1111/j.1744-313x.1976.tb00588.x.
Two children in a family were found to be homozygous for C2 deficiency; both parents and a third child were heterozygous. C2 deficiency was associated with the HLA haplotypes carrying the antigens B18 and DW2. Antigen A10 was absent in this family. Mixed lymphocyte culture studies among the family members confirmed the association of C2 deficiency with the HLA-D locus.
一个家庭中的两个孩子被发现为C2缺陷纯合子；父母双方和第三个孩子为杂合子。C2缺陷与携带抗原B18和DW2的HLA单倍型相关。该家庭中不存在抗原A10。家庭成员间的混合淋巴细胞培养研究证实了C2缺陷与HLA - D位点的相关性。
