林丹对欧洲鳗鲡碳水化合物代谢的影响。

Lindane-induced changes in carbohydrate metabolism in Anguilla anguilla.

Ferrando M D, Andreu-Moliner E

Department of Animal Physiology, Faculty of Biological Sciences, University of Valencia, Spain.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Feb;101(2):437-41. doi: 10.1016/0742-8413(92)90300-v.

Abstract

Anguilla anguilla (L.) was exposed to a sublethal concentration of 0.167 ppm (0.25 of the 96-hr LC50) of lindane for 6, 12, 24, 48, 72 and 96 hr. 2. Changes in glycogen, glucose, pyruvate and lactate contents of liver and muscle after lindane exposure, were studied. 3. Muscle and liver glycogen levels decreased significantly during the exposure time. Muscle glucose values increased but on the other hand we found a decrease in those of liver. 4. Muscle and liver pyruvate content increased as did lactate levels in both tissues. 5. The observed effects of lindane on carbohydrate metabolism in fish are discussed in relation to acute stress syndrome.

摘要

将欧洲鳗鲡（Anguilla anguilla (L.)）暴露于浓度为0.167 ppm（96小时半数致死浓度的0.25）的林丹中6、12、24、48、72和96小时。2. 研究了林丹暴露后肝脏和肌肉中糖原、葡萄糖、丙酮酸和乳酸含量的变化。3. 在暴露期间，肌肉和肝脏中的糖原水平显著下降。肌肉中的葡萄糖值升高，而肝脏中的葡萄糖值则下降。4. 肌肉和肝脏中的丙酮酸含量增加，两个组织中的乳酸水平也增加。5. 结合急性应激综合征讨论了林丹对鱼类碳水化合物代谢的观察效应。