Sancho E, Ferrando M D, Andreu E
Department of Animal Physiology, Faculty of Biological Sciences, University of Valencia, Spain.
Ecotoxicol Environ Saf. 1997 Feb;36(1):57-65. doi: 10.1006/eesa.1996.1488.
The present communication deals with the effects of fenitrothion (0.02 mg/liter) on the energy metabolism of the European eel, Anguilla anguilla, and its recovery from intoxication. Various parameters such as glycogen, lactate, proteins, and glucose levels were measured in different eel tissues after 2, 8, 12, 24, 32, 48, 56, 72, and 96 hr of fenitrothion exposure. Subsequently, the fish were allowed recovery periods of 8, 12, 24, 48, 72, 96, 144, and 192 hr in clean water, and the same parameters were evaluated. Liver glycogen content showed no significant changes during the exposure time, while blood glucose levels increased markedly. Gill, liver, and blood lactate values increased during pesticide exposure, while proteins decreased in comparison to unexposed controls. Most of the metabolic disorders did not persist after eels were allowed to recover in clean water for less than a week. The observed effects of fenitrothion on fish metabolism are discussed in relation to a stress syndrome, as are probable reasons for alterations.
本通讯探讨了杀螟硫磷（0.02毫克/升）对欧洲鳗鲡（Anguilla anguilla）能量代谢及其从中毒状态恢复的影响。在杀螟硫磷暴露2、8、12、24、32、48、56、72和96小时后，测定了不同鳗鲡组织中的各种参数，如糖原、乳酸、蛋白质和葡萄糖水平。随后，让鱼在清洁水中恢复8、12、24、48、72、96、144和192小时，并评估相同的参数。肝脏糖原含量在暴露期间没有显著变化，而血糖水平显著升高。鳃、肝脏和血液中的乳酸值在农药暴露期间增加，而与未暴露的对照组相比，蛋白质减少。在鳗鲡在清洁水中恢复不到一周后，大多数代谢紊乱并未持续。讨论了杀螟硫磷对鱼类代谢的观察到的影响与应激综合征的关系，以及变化的可能原因。
