Mitrofanis J
Department of Human Anatomy, University of Oxford, UK.
J Neurocytol. 1992 Jul;21(7):495-505. doi: 10.1007/BF01186953.
Recent studies have shown that the thalamic reticular nucleus of cats is made up of several cytoarchitectonically distinct subdivisions and that the nucleus contains accurate topographical maps of the cortical sheet and of the dorsal thalamus. The present study describes immunocytochemically demonstrable heterogeneity in the reticular nucleus of cats, with an antibody to calbindin D28k. The striking feature of calbindin immunoreactivity in the reticular nucleus of cats is that the immunoreactive neurones are located in the caudal half of the nucleus only. In these regions, labelled cells form a small proportion of the total population of reticular cells only and are not distinct in somal size or shape from neighbouring non-labelled reticular cells. Double labelling shows that the calbindin-immunoreactive cells are also immunoreactive to parvalbumin and GABA. There is a distinct tendency for the calbindin-immunoreactive cells to be more numerous ventrally than dorsally in the caudal half of the nucleus, which receives afferents from the somatosensory and auditory systems.
最近的研究表明，猫的丘脑网状核由几个细胞构筑上不同的亚区组成，并且该核包含皮质层和背侧丘脑的精确地形图。本研究用抗钙结合蛋白D28k的抗体描述了猫网状核中免疫细胞化学可证实的异质性。猫网状核中钙结合蛋白免疫反应性的显著特征是，免疫反应性神经元仅位于核的后半部分。在这些区域，标记细胞仅占网状细胞总数的一小部分，并且在体细胞大小或形状上与相邻的未标记网状细胞没有区别。双重标记显示，钙结合蛋白免疫反应性细胞对小白蛋白和GABA也有免疫反应性。在接受来自体感和听觉系统传入纤维的核的后半部分，钙结合蛋白免疫反应性细胞在腹侧比背侧数量更多，这有明显的趋势。
