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小唾液腺多形性腺瘤中S-100蛋白分布的免疫组织化学研究

Immunohistochemical study of the distribution of S-100 protein in pleomorphic adenomas of minor salivary glands.

作者信息

Siar C H, Ng K H

机构信息

Department of Oral Pathology and Oral Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

J Nihon Univ Sch Dent. 1992 Jun;34(2):96-105. doi: 10.2334/josnusd1959.34.96.

DOI:10.2334/josnusd1959.34.96
PMID:1380072
Abstract

Twelve pleomorphic adenomas of minor salivary gland origin were examined for the distribution of S-100 protein, detected using the peroxidase-antiperoxidase (PAP) method. Strong S-100 protein immunoreactivity was noted in areas containing plasmacytoid cells, stellate and spindle cells against a myxochondroid or hyalinous stroma, and solid epithelial areas. Tubular and duct-like structures showed variable stainability. Stromal tissue and normal salivary glands were generally negative for S-100 protein. These findings were compared with those reported elsewhere.

摘要

对12例起源于小唾液腺的多形性腺瘤进行了研究,采用过氧化物酶抗过氧化物酶(PAP)法检测S-100蛋白的分布。在含有浆细胞样细胞、星状和梭形细胞的区域,相对于黏液软骨样或透明样基质以及实性上皮区域,观察到强烈的S-100蛋白免疫反应性。管状和导管样结构显示出不同的染色性。基质组织和正常唾液腺通常对S-100蛋白呈阴性。将这些结果与其他地方报道的结果进行了比较。

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