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[高山条件下放射性损伤的临床病程]

[Clinical course of a radiation lesion under high-mountain conditions].

作者信息

Grigor'ev Iu G, Daniiarov S B, Mirrakhimov M M, Farber Iu V, Kalandarova M P

出版信息

Kosm Biol Aviakosm Med. 1976 Nov-Dec;10(6):51-4.

PMID:138024
Abstract

The development and outcome of radiation disease were studied on dogs kept at an altitude of 3200 m above sea level. Clinical observations, morphological examinations of blood and bone marrow and measurements of blood coagulation parameters were carried out at different time intervals. Our findings demonstrated that irradiation of animals that followed a 25-day altitude acclimatization and their subsequent exposure to an altitude alleviated radiation disease. The clinical course of radiation disease aggravated in dogs that were reacclimatized to highlands after irradiation. It can be postulated that the dogs kept in highlands before and after irradiation developed a more intensive process of restoration, especially of erythropoiesis. They also showed a stable decrease of the blood coagulation rate and long persistence of high fibrinolytic activity of the blood.

摘要

对饲养在海拔3200米处的犬只的辐射病发展及预后进行了研究。在不同时间间隔进行了临床观察、血液和骨髓的形态学检查以及血液凝固参数测量。我们的研究结果表明,经过25天海拔适应后接受照射并随后暴露于高海拔环境的动物,其辐射病得到缓解。照射后重新适应高原环境的犬只,其辐射病临床病程加重。可以推测,照射前后饲养在高原的犬只形成了更强烈的恢复过程,尤其是红细胞生成过程。它们还表现出血液凝固率稳定下降以及血液高纤溶活性长期持续。

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1
[Clinical course of a radiation lesion under high-mountain conditions].[高山条件下放射性损伤的临床病程]
Kosm Biol Aviakosm Med. 1976 Nov-Dec;10(6):51-4.
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