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鼻过敏中的杯状细胞(作者译)

[Goblet cells in nasal allergy (author's transl)].

作者信息

Mogensen C, Tos M

出版信息

Laryngol Rhinol Otol (Stuttg). 1976 Dec;55(12):955-61.

PMID:138036
Abstract

After staining of the whole nasal mucosa from a patient with nasal allergy by the PAS-alcian-blue whole mount method, the density of goblet cells was determined quantitatively. In most sections of the nasal septum and of the inferior and middle nasal concha, the density of goblet cells was found to be considerably lower than in normal subjects. While in some sections, in particular posteriorly, the density was the same as in normal subjects, it was nowhere higher. The low density may be due to metaplastic changes of the epithelium which had thickened and lost ciliary cells. Previous statements that the density of goblet cells is increased in nasal allergy could not be confirmed quantitatively, but investigation of larger materials is called for before any conclusions may be drawn.

摘要

采用过碘酸-阿尔辛蓝整装法对一名鼻过敏患者的整个鼻黏膜进行染色后,对杯状细胞密度进行了定量测定。在鼻中隔以及下鼻甲和中鼻甲的大多数切片中,发现杯状细胞密度明显低于正常受试者。虽然在某些切片中,特别是后部,密度与正常受试者相同,但 nowhere higher(此处可能有误,推测可能是“没有更高的情况”)。密度较低可能是由于上皮发生化生改变,上皮增厚并失去了纤毛细胞。之前关于鼻过敏时杯状细胞密度增加的说法无法得到定量证实,但在得出任何结论之前,需要对更多材料进行研究。

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Laryngol Rhinol Otol (Stuttg). 1976 Dec;55(12):955-61.
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