Bank S, Abrol R P, Greenberg R, Blumstein M, Kranz V
Division of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park, NY 11040.
Int J Pancreatol. 1992 Jun;11(3):191-4. doi: 10.1007/BF02924185.
Single random samples of urine were collected from 50 control subjects; 27 patients with chronic pancreatitis; 19 with acute pancreatitis; 6 with acute on chronic pancreatitis; five in the recovery phase of acute attack; four patients with pseudocysts. Salivary (S) and pancreatic (P) amylase values were measured by cellulose acetate electrophoresis. The P amylase values always exceeded those of S amylase in the control specimens. In acute pancreatitis, both the lower and upper levels of total and P amylase were considerably higher than in the controls, and these high values tended to return to normal during the recovery phase of acute pancreatitis. The S amylase values were often very low or undetectable during the acute phase. Values for P amylase exceeded control values in patients with pseudocysts even in the presence of chronic pancreatitis. In chronic calcific pancreatitis, S amylase was higher than P amylase. We conclude that P amylase is always greater than S amylase in normal urine specimens, and a change in this pattern may be helpful in diagnosing various forms of pancreatitis.
从50名对照受试者、27例慢性胰腺炎患者、19例急性胰腺炎患者、6例慢性胰腺炎急性发作患者、5例急性发作恢复期患者以及4例胰腺假性囊肿患者中采集单次随机尿样。通过醋酸纤维素电泳测量唾液淀粉酶（S）和胰腺淀粉酶（P）值。在对照样本中，P淀粉酶值始终超过S淀粉酶值。在急性胰腺炎中，总淀粉酶和P淀粉酶的下限和上限均显著高于对照组，且这些高值在急性胰腺炎恢复期往往会恢复正常。在急性期，S淀粉酶值通常非常低或无法检测到。即使存在慢性胰腺炎，胰腺假性囊肿患者的P淀粉酶值也超过对照值。在慢性钙化性胰腺炎中，S淀粉酶高于P淀粉酶。我们得出结论，在正常尿样中，P淀粉酶始终大于S淀粉酶，这种模式的改变可能有助于诊断各种形式的胰腺炎。
