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肺炎链球菌对层粘连蛋白、IV型胶原和玻连蛋白的结合

Binding of laminin, type IV collagen, and vitronectin by Streptococcus pneumoniae.

作者信息

Kostrzynska M, Wadström T

机构信息

Department of Medical Microbiology, University of Lund, Sweden.

出版信息

Zentralbl Bakteriol. 1992 Jun;277(1):80-3. doi: 10.1016/s0934-8840(11)80874-1.

DOI:10.1016/s0934-8840(11)80874-1
PMID:1381646
Abstract

Forty-three strains of Streptococcus pneumoniae were tested for their ability to bind radiolabelled laminin, collagen types I, II and IV, fibronectin, and vitronectin. Two basement membrane components, laminin and type IV collagen, interacted with many S. pneumoniae strains. All strains bound laminin and 28 (65%) bound collagen type IV. Approximately 60% of the strains bound vitronectin but only a few strains showed low binding of fibronectin and collagen type I and II.

摘要

对43株肺炎链球菌进行了检测,以评估它们结合放射性标记的层粘连蛋白、I型、II型和IV型胶原蛋白、纤连蛋白以及玻连蛋白的能力。两种基底膜成分,即层粘连蛋白和IV型胶原蛋白,与许多肺炎链球菌菌株发生相互作用。所有菌株都能结合层粘连蛋白,28株(65%)能结合IV型胶原蛋白。约60%的菌株能结合玻连蛋白,但只有少数菌株对纤连蛋白以及I型和II型胶原蛋白的结合能力较低。

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