Khamidov D Kh, Marakhmedov A K, Sagatova G A, Azimova Sh S
Biull Eksp Biol Med. 1992 Jan;113(1):40-2.
The experiments on the investigation of pesticide cotoran-effect on RNA synthesis and transport were carried out. Cotoran was shown to destroy considerably the processes of RNA biosynthesis in rat liver, that results in the decrease of RNA transport from nuclei into cytoplasm. By special experiments it was established that functional activity and the integrity of nuclear membrane (according to the alteration in the activity of nuclear membrane enzyme Mg2-dependent ATP-ase) was not destroyed.
开展了关于农药克菌丹对RNA合成和转运影响的研究实验。结果表明，克菌丹能显著破坏大鼠肝脏中RNA的生物合成过程，导致RNA从细胞核向细胞质的转运减少。通过特殊实验确定，核膜的功能活性和完整性（根据核膜酶Mg2+依赖的ATP酶活性的变化）并未遭到破坏。
