Sakamoto M, Katayama T, Umeda K, Kazama T, Terada T, Fuse H
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University.
Hinyokika Kiyo. 1992 Aug;38(8):907-11.
Between 1984 and 1990, a mass screening for prostatic diseases was carried out on men over 55 years old in cities, towns and villages in Toyama Prefecture, Japan. The total number of subjects examined in the primary study was 1,232, which was 17.7% of the males over 55 years old in these areas. The primary study consisted of inquiry concerning urination, digital examination of the prostate, transabdominal ultrasonography, and determination of tumor markers. A secondary study was indicated for 100 subjects (8.9%) suspected to have prostatic cancer and 169 (15%) suspected to have benign prostatic hypertrophy, but only 92 (35%) of them were actually examined. Prostatic cancer was histologically diagnosed in 3 subjects (0.3%), and benign prostatic hypertrophy was established in 56 subjects (4.5%), who were referred to urologists. Though a high percentage of the population was covered by the primary study the percentage of subjects who received the secondary study among those in whom it was indicated was low. This probably was a reason for the low detection rate of prostatic cancer. An improved system is considered to be needed to increase the efficiency of mass screening for prostatic diseases.
1984年至1990年期间，在日本富山县的城市、城镇和乡村对55岁以上男性进行了前列腺疾病大规模筛查。初步研究中接受检查的对象总数为1232人，占这些地区55岁以上男性的17.7%。初步研究包括排尿询问、前列腺指诊、经腹超声检查以及肿瘤标志物测定。对100名疑似前列腺癌的对象（8.9%）和169名疑似良性前列腺增生的对象（15%）进行了二次检查，但实际接受检查的只有92人（35%）。经组织学诊断，有3名对象患前列腺癌（0.3%），56名对象患良性前列腺增生（4.5%），这些对象被转诊给泌尿科医生。尽管初步研究覆盖了很大比例的人群，但在那些被建议进行二次检查的对象中，实际接受二次检查的比例较低。这可能是前列腺癌检出率低的一个原因。为提高前列腺疾病大规模筛查的效率，认为需要改进筛查体系。
