两种伯基特淋巴瘤细胞系中的变异易位位于MLV14基因座。
Variant translocations in two Burkitt's lymphoma cell lines are located in the MLV14 locus.
作者信息
Gallego M I, Lazo P A
机构信息
Unidad de Genética Molecular, Instituto de Salud Carlos III, Majadahonda, Spain.
出版信息
Genes Chromosomes Cancer. 1992 Oct;5(3):267-9. doi: 10.1002/gcc.2870050317.
PMID:1384683
Abstract
The human MLV14 locus, located 20 kilobases 3' of MYC, is rearranged in two Burkitt's lymphoma cell lines with either a t(2;8)(p12;q24) or t(8;22)(q24;q11). Alterations of MLV14 may have prognostic significance in some types of B-cell malignancies.
摘要
人类MLV14基因座位于MYC基因下游20千碱基处，在两个患有t(2;8)(p12;q24)或t(8;22)(q24;q11)的伯基特淋巴瘤细胞系中发生了重排。MLV14的改变可能在某些类型的B细胞恶性肿瘤中具有预后意义。
Zotero 插件