Romics I, Galamb L
Department of Urology, Semmelweis Medical University, Budapest, Hungary.
Eur Urol. 1992;21 Suppl 1:83-6. doi: 10.1159/000474898.
The authors measured serum prostate-specific antigen (PSA) and prostatic acid phosphatase concentration in histologically positive prostate hyperplastic and carcinomatous patients before, and 30-60 min and 24 h after prostate manipulation (rectal digital examination, cystoscopy and perineal punch biopsy). After rectal examination, PSA, and after other interventions, both markers changed significantly, although in different points of time and to a different extent. The authors call the attention to the importance of the point of time of the examination. Examination following prostate manipulation may result in wrong diagnosis or in erroneous therapeutic consequences in the follow-up period.
作者测量了组织学确诊的前列腺增生和癌患者在前列腺操作（直肠指检、膀胱镜检查和会阴穿刺活检）前、操作后30 - 60分钟及24小时的血清前列腺特异性抗原（PSA）和前列腺酸性磷酸酶浓度。直肠检查后PSA会发生变化，而在其他干预措施后，两种标志物均有显著变化，尽管变化的时间点和程度不同。作者提醒注意检查时间点的重要性。前列腺操作后的检查可能会导致错误诊断或在随访期产生错误的治疗后果。
