Romano V, Raimondi E, Bosco P, Feo S, Di Pietro C, Leube R E, Troyanovsky S M, Ceratto N
Laboratorio di Genetica Molecolare, OASI Istituto per la Ricerca sul Ritardo Mentale e l'Involuzione Cerebrale (IRCCS), Troina, Italy.
Genomics. 1992 Oct;14(2):495-7. doi: 10.1016/s0888-7543(05)80250-2.
In the present study the human cytokeratin 13 gene (KRT13), encoding a polypeptide characteristic of internal stratified epithelia, has been mapped with the help of the polymerase chain reaction and somatic cell hybrids to chromosome 17. In situ hybridization of a KRT13 cDNA probe to metaphase chromosomes allowed the assignment of the KRT13 gene within the q12-q21.2 region of chromosome 17.
在本研究中,编码内分层上皮特征性多肽的人细胞角蛋白13基因(KRT13),借助聚合酶链反应和体细胞杂种被定位到了17号染色体上。用KRT13 cDNA探针与中期染色体进行原位杂交,可将KRT13基因定位于17号染色体的q12 - q21.2区域内。