人类NK-2受体基因定位于染色体区域10q11 - 21。
Human NK-2 receptor gene maps to chromosome region 10q11-21.
作者信息
Morten J E, Hopkins B, Powell S J, Graham A
机构信息
Biotechnology Department, ICI Pharmaceuticals, Alderley Park, Macclesfield, UK.
出版信息
Hum Genet. 1991 Dec;88(2):200-3. doi: 10.1007/BF00206072.
PMID:1661704
Abstract
The human NK-2 receptor gene has been mapped to chromosome 10 using the polymerase chain reaction to amplify specifically the human NK-2 receptor sequence in hamster/human hybrid DNA and also in mouse/human monochromosome hybrids. The assignment to chromosome 10 was confirmed by in situ hybridisation to human metaphase chromosomes, giving a regional localisation of 10q11-21.
摘要
利用聚合酶链反应特异性扩增仓鼠/人类杂交DNA以及小鼠/人类单染色体杂交体中的人类NK-2受体序列，已将人类NK-2受体基因定位于10号染色体。通过对人类中期染色体进行原位杂交，证实该基因定位于10号染色体，区域定位为10q11 - 21。
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