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Escherichia coli integration host factor stabilizes bacteriophage Mu repressor interactions with operator DNA in vitro.

作者信息

Alazard R, Bétermier M, Chandler M

机构信息

Centre de Recherches en Biochimie et Génétique Cellulaires, Toulouse, France.

出版信息

Mol Microbiol. 1992 Jun;6(12):1707-14. doi: 10.1111/j.1365-2958.1992.tb00895.x.

DOI:10.1111/j.1365-2958.1992.tb00895.x
PMID:1386645
Abstract

Using gel retardation and DNase I protection techniques, we have demonstrated that the Escherichia coli integration host factor (IHF) stabilizes the interaction between Mu repressor and its cognate operator-binding sites in vitro. These results are discussed in terms of a model in which IHF may commit the phage to the lytic or lysogenic pathway depending on the occupancy of the operator sites by the repressor.

摘要

相似文献

1
Escherichia coli integration host factor stabilizes bacteriophage Mu repressor interactions with operator DNA in vitro.
Mol Microbiol. 1992 Jun;6(12):1707-14. doi: 10.1111/j.1365-2958.1992.tb00895.x.
2
Stabilization of bacteriophage Mu repressor-operator complexes by the Escherichia coli integration host factor protein.
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The integration host factor-DNA complex upstream of the early promoter of bacteriophage Mu is functionally symmetric.噬菌体Mu早期启动子上游的整合宿主因子-DNA复合物在功能上是对称的。
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引用本文的文献

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Controlling DNA degradation from a distance: a new role for the Mu transposition enhancer.远距离控制DNA降解：Mu转座增强子的新作用。
Mol Microbiol. 2014 Nov;94(3):595-608. doi: 10.1111/mmi.12781. Epub 2014 Sep 25.
2
Coactivation in vitro of the sigma54-dependent promoter Pu of the TOL plasmid of Pseudomonas putida by HU and the mammalian HMG-1 protein.恶臭假单胞菌TOL质粒的sigma54依赖性启动子Pu在体外被HU和哺乳动物HMG-1蛋白共激活。
J Bacteriol. 1997 Apr;179(8):2757-60. doi: 10.1128/jb.179.8.2757-2760.1997.
3
Phage HK022 Roi protein inhibits phage lytic growth in Escherichia coli integration host factor mutants.
噬菌体HK022的Roi蛋白抑制噬菌体在大肠杆菌整合宿主因子突变体中的裂解生长。
J Bacteriol. 1996 Jul;178(14):4077-83. doi: 10.1128/jb.178.14.4077-4083.1996.
4
Regulatory factors acting at the bacteriophage Mu middle promoter.作用于噬菌体Mu中间启动子的调控因子。
J Bacteriol. 1996 Mar;178(6):1585-92. doi: 10.1128/jb.178.6.1585-1592.1996.
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Involvement of Escherichia coli FIS protein in maintenance of bacteriophage mu lysogeny by the repressor: control of early transcription and inhibition of transposition.大肠杆菌FIS蛋白通过阻遏物参与噬菌体μ溶原性的维持：早期转录的控制和转座的抑制
J Bacteriol. 1993 Jun;175(12):3798-811. doi: 10.1128/jb.175.12.3798-3811.1993.
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Microbiol Rev. 1994 Jun;58(2):268-90. doi: 10.1128/mr.58.2.268-290.1994.
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J Bacteriol. 1994 Nov;176(22):6795-801. doi: 10.1128/jb.176.22.6795-6801.1994.
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Genetica. 1994;93(1-3):27-39. doi: 10.1007/BF01435237.
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Use of gel retardation to analyze protein-nucleic acid interactions.使用凝胶阻滞分析法分析蛋白质-核酸相互作用。
Microbiol Rev. 1992 Dec;56(4):509-28. doi: 10.1128/mr.56.4.509-528.1992.