Gabriel R, Leroux B, Quéreux C, Daoud S, Wahl P
Department of Obstetrics and Gynecology, Hopital Maison Blanche, Reims, France.
Eur J Obstet Gynecol Reprod Biol. 1992 Jul 3;45(2):101-5. doi: 10.1016/0028-2243(92)90224-m.
In order to assess the contribution of antenatal diagnosis to the management of gastroschisis, the antenatal and postnatal data from 24 cases of gastroschisis observed between 1974 and 1990 were re-examined. The frequency of antenatal diagnosis (29%), polyhydramnios (21%), atresia of the small intestine (29%), length of pregnancy (36.6 +/- 2 weeks of amenorrhea), proportion of cesarean sections (21%), birth weight (2230 +/- 430 g) and the Apgar score after 5 min (9.0 +/- 1.5) were comparable to findings reported elsewhere. The overall mortality rate for the period studied was high (41%), and was not influenced by any antenatal parameter or by the mode of delivery; its recent fall (P = 0.01) is explained by the development of therapeutic methods. These results are consistent with other recent studies and suggest that antenatal diagnosis does not enable an accurate assessment of the prognosis to be made and has no major influence on the mortality rate in gastroschisis.
为评估产前诊断对腹裂治疗的作用，我们重新审视了1974年至1990年间观察到的24例腹裂病例的产前和产后数据。产前诊断频率（29%）、羊水过多（21%）、小肠闭锁（29%）、妊娠时长（闭经36.6±2周）、剖宫产比例（21%）、出生体重（2230±430克）以及5分钟后的阿氏评分（9.0±1.5）与其他地方报道的结果相当。所研究期间的总体死亡率较高（41%），且不受任何产前参数或分娩方式的影响；其近期下降（P = 0.01）是治疗方法发展的结果。这些结果与近期其他研究一致，表明产前诊断无法准确评估预后，对腹裂死亡率也没有重大影响。
