Poulain P, Milon J, Frémont B, Proudhon J F, Odent S, Babut J M, Le Marec B, Grall J Y, Giraud J R
Department of Obstetrics and Gynecology, CHRU Rennes, France.
Eur J Obstet Gynecol Reprod Biol. 1994 May 18;54(3):185-90. doi: 10.1016/0028-2243(94)90280-1.
We report our experience of 15 cases of gastroschisis which occurred between 1981 and 1993. All but one were diagnosed antenatally by ultrasound between 16 and 32 weeks of pregnancy. We made a termination of the pregnancy in 3 cases, for multiple malformations in 2 cases and one case of very early premature rupture of the membranes (PROM). When checked (11 cases), the karyotype was normal. We made a cesarean section in 11 cases: the indication was a complication for 6 (fetal distress, PROM, polyhydramnios, large dilatation of the gut). We noted growth retardation in 7 newborns and prematurity in 5/12 (mean gestational age of 36.8 weeks). The preoperative study of the gut noted 5 cases with intestinal damage and one case of complete necrosis of the gut. The global prognosis is not as good as usual, with a perinatal mortality of 41.6% (5/12). We discuss this latter point and examine the literature.
我们报告了1981年至1993年间发生的15例腹裂病例的经验。除1例外，所有病例均在妊娠16至32周期间通过超声产前诊断。我们对3例妊娠进行了终止，其中2例因多发畸形，1例因胎膜过早破裂（PROM）。在进行检查的11例中，核型正常。我们对11例进行了剖宫产：其中6例的指征为并发症（胎儿窘迫、PROM、羊水过多、肠道大扩张）。我们注意到7例新生儿生长发育迟缓，12例中有5例早产（平均孕周36.8周）。术前对肠道的检查发现5例肠道损伤，1例肠道完全坏死。总体预后不如往常，围产期死亡率为41.6%（5/12）。我们讨论了这一点并查阅了文献。
