Mossalayi D, Dalloul A, Arock M, Debre P
Lab. Immunologie Cellulaire URA CNRS Pitie Salpetriere, France.
Bone Marrow Transplant. 1992;9 Suppl 1:50-3.
We report herein the effect of soluble CD23 (sCD23) on the differentiation of lymphoid and myeloid precursors. CD23 is known as the low affinity receptor for IgE. In addition to it, our results indicate that sCD23 in synergy with IL1 is able to promote the maturation of normal and leukemic hematopoietic progenitor cells.
我们在此报告可溶性CD23(sCD23)对淋巴样和髓样前体细胞分化的影响。CD23被认为是IgE的低亲和力受体。除此之外,我们的结果表明,sCD23与IL1协同作用能够促进正常和白血病造血祖细胞的成熟。