[Soluble CD23: cytokine actives on human hematopoietic precursors].
作者信息
Mossalayi M D, Dalloul A H, Debré P
机构信息
Laboratoire d'Immunologie Cellulaire et Tissulaire, CNRS URA 625, Hôpital Pitié-Salpêtrière, Paris, France.
出版信息
C R Seances Soc Biol Fil. 1991;185(4):198-205.
PMID:1836414
Abstract
We report herein the effect of soluble CD23 (sCD23) on the differentiation of early lymphoid and myeloid human precursors. CD23 is known as a low affinity receptor for IgE. In addition, our results show that sCD23 in synergy with IL1 has a potent activity on the maturation of prothymocytes and the proliferation of multipotential normal and leukemic myeloid precursors.
摘要
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