Davidorf J, Davidorf F
Department of Ophthalmology, Ohio State University, Columbus 43210.
Ophthalmic Surg. 1992 Aug;23(8):522-7.
Photodynamic therapy was used to treat four patients with iris melanoma. Hematoporphyrin derivative was used as a sensitizing agent. The tumors were exposed to a total dose of 1.72 x 10(6) J/cm2 of 630-nanometer laser light. The eye of the first patient, enucleated after treatment, histopathologically showed significant tumor necrosis. The tumors in the three subsequent patients were almost completely ablated, with no evidence of regrowth.
采用光动力疗法治疗4例虹膜黑色素瘤患者。以血卟啉衍生物作为光敏剂。用630纳米的激光对肿瘤进行照射，总剂量为1.72×10⁶焦/平方厘米。首例患者在治疗后摘除眼球，病理组织学检查显示肿瘤有明显坏死。随后3例患者的肿瘤几乎完全被消融，无复发迹象。
