BRACKENRIDGE C J
J Clin Pathol. 1962 May;15(3):206-10. doi: 10.1136/jcp.15.3.206.
Samples of lumbar cerebrospinal fluid from 20 healthy subjects and 20 patients with a variety of neurological disorders have been subjected to cellulose acetate electrophoresis and quantitative analyses carried out on the seven separated protein fractions. Normal percentage and absolute concentration limits for each fraction have been determined and compared with previous reports. It is concluded that absolute values are more valuable than percentage values in the discrimination of disease from health, but that the mechanisms governing protein abnormalities are difficult to ascertain from spinal fluid electrophoresis alone.
对20名健康受试者和20名患有各种神经系统疾病的患者的腰椎脑脊液样本进行了醋酸纤维素电泳,并对七个分离的蛋白质组分进行了定量分析。已确定每个组分的正常百分比和绝对浓度限值,并与先前的报告进行了比较。得出的结论是,在区分疾病与健康方面,绝对值比百分比值更有价值,但仅从脑脊液电泳很难确定蛋白质异常的机制。