Knussmann R, Christiansen K, Kannmacher J
Institut für Humanbiologie, University of Hamburg, Germany.
Am J Phys Anthropol. 1992 May;88(1):59-67. doi: 10.1002/ajpa.1330880106.
Total testosterone and dihydrotestosterone in blood serum as well as free testosterone in saliva were determined by radioimmunoassay in 110 healthy young men. The results were compared with the development of terminal hair on the trunk and limbs, with the disposition to balding and with the disposition to acne. No significant correlations were found between terminal hair development and absolute androgen levels; however, some significant values were observed in the case of the metabolic rate of dihydrotestosterone/testosterone and the proportion of free to total testosterone. The disposition to balding also correlates positively with the latter ratio. Yet the absolute serum androgen concentrations in men with a disposition to balding is lower than in men with no reduction of scalp hair. The widespread assumption that androgen levels are in general elevated in bald-trait men must therefore be rejected. In accordance with this finding, men with a disposition to balding are morphologically (with regard to anthropometric measures) no more masculine than those with good scalp hair growth. When body build and age are taken into consideration, the relations between terminal hair and androgen ratio are also problematical. No relationship could be found between acne and androgens.
采用放射免疫分析法检测了110名健康年轻男性血清中的总睾酮和双氢睾酮以及唾液中的游离睾酮。将结果与躯干和四肢终毛的生长情况、脱发倾向以及痤疮倾向进行了比较。终毛生长与雄激素绝对水平之间未发现显著相关性;然而,在双氢睾酮/睾酮代谢率以及游离睾酮与总睾酮的比例方面观察到了一些显著值。脱发倾向也与后一比例呈正相关。然而,有脱发倾向的男性血清雄激素绝对浓度低于无头皮毛发减少的男性。因此,必须摒弃普遍认为具有脱发特征的男性雄激素水平普遍升高这一假设。根据这一发现,有脱发倾向的男性在形态上(就人体测量指标而言)并不比头皮毛发良好的男性更具男性特征。当考虑体型和年龄时,终毛与雄激素比例之间的关系也存在问题。痤疮与雄激素之间未发现关联。