Boo N Y
Department of Paediatrics, Universiti Kebangsaan Malaysia.
Med J Malaysia. 1992 Mar;47(1):56-9.
A prospective study was carried out in the Maternity Hospital, Kuala Lumpur in 1989 to determine the morbidity and mortality of infants of diabetic mothers. Out of 24,856 neonates born during the study period, 54 neonates (2.2 per 1000 livebirths) were born to mothers who were diagnosed to have diabetes mellitus before the current pregnancy or who had impaired glucose tolerance test during the current pregnancy. Almost a third (29.6 percent) of these infants of diabetic mothers had birthweight of 4000 grams and above, and 37.0 percent of the 54 babies were large-for-gestational age. Hypoglycemia occurred in 9/54 (16.7 percent) of the neonates, respiratory distress syndrome in 5/54 (9.3 percent), shoulder dystocia in 7/54 (13.0 percent), and congenital abnormalities in 4/54 (7.4 percent). Three (5.6 percent) neonates died during the neonatal period. The results of this study suggest a need to intensify control of maternal diabetes mellitus during pregnancy in order to reduce the rates of morbidity and mortality of their infants.
1989年在吉隆坡妇产医院进行了一项前瞻性研究，以确定糖尿病母亲所生婴儿的发病率和死亡率。在研究期间出生的24,856名新生儿中，有54名新生儿（每1000例活产中有2.2例）的母亲在本次怀孕前被诊断患有糖尿病，或在本次怀孕期间葡萄糖耐量试验受损。这些糖尿病母亲所生的婴儿中，近三分之一（29.6%）出生体重达到或超过4000克，在这54名婴儿中，37.0%为大于胎龄儿。9/54（16.7%）的新生儿发生低血糖，5/54（9.3%）发生呼吸窘迫综合征，7/54（13.0%）发生肩难产，4/54（7.4%）有先天性异常。3名（5.6%）新生儿在新生儿期死亡。本研究结果表明，需要在孕期加强对母亲糖尿病的控制，以降低其婴儿的发病率和死亡率。
