糖尿病母亲所生婴儿的围产期结局

Perinatal outcome of infants born to diabetic mothers.

作者信息

Deorari A K, Kabra S K, Paul V K, Singh M

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi.

出版信息

Indian Pediatr. 1991 Nov;28(11):1271-5.

PMID:1808047

Abstract

Two hundred and sixty three pregnant diabetic mothers' perinatal outcome was evaluated. Two hundred and twenty five infants were born to gestational diabetic mothers (IGDM) and 38 infants to mothers with established diabetes mellitus (IDM). In IGDM group, 34 babies (15%) were preterm and 45 (20%) were low birth weight (less than 2500 g). Thirty eight babies (17%) were large-for-dates (LFD) and 14 (6.2%) were small-for-dates (SFD). Among IDM group, 8 (21%) babies were preterm and 8 (21%) were low birth weight (less than 2500 g). Fifteen babies (39.5%) were LFD and 3 (8%) were SFD. Out of all babies, hypoglycemia occurred in 43 (16%), birth asphyxia in 24 (9%) and respiratory distress in 21 (8%). Nearly half of respiratory distress were due to hyaline membrane disease. Perinatal mortality rate was significantly higher (p less than 0.001) in IDM (237/1000 live birth) as compared to IGDM (40/1000 live birth).

摘要

对263名糖尿病孕妇的围产期结局进行了评估。225名婴儿为妊娠期糖尿病母亲（IGDM）所生，38名婴儿为患有已确诊糖尿病的母亲（IDM）所生。在IGDM组中，34名婴儿（15%）早产，45名（20%）出生体重低（低于2500克）。38名婴儿（17%）为大于胎龄儿（LFD），14名（6.2%）为小于胎龄儿（SFD）。在IDM组中，8名婴儿（21%）早产，8名（21%）出生体重低（低于2500克）。15名婴儿（39.5%）为LFD，3名（8%）为SFD。在所有婴儿中，43名（16%）出现低血糖，24名（9%）出现出生窒息，21名（8%）出现呼吸窘迫。近一半的呼吸窘迫是由于肺透明膜病所致。与IGDM（40/1000活产）相比，IDM的围产儿死亡率显著更高（p<0.001）（237/1000活产）。