Kershenovich J, Langenberg A, Odom R B, LeBoit P E
Department of Dermatology, University of California, San Francisco 94143.
J Am Acad Dermatol. 1992 Aug;27(2 Pt 2):345-8. doi: 10.1016/0190-9622(92)70197-n.
We describe a patient with clinical features that resembled severe chloracne; however, histopathologic findings revealed a reticulated pigmented anomaly. Innumerable comedones, many cysts, acneiform scarring, and flexural and facial pigmentation were noted in this patient, who is a machinist. A serum test for polychlorinated biphenyl was negative, which eliminated a diagnosis of chloracne. The spectrum of clinical features of the histologically well-defined Dowling-Degos' disease is discussed; in this disease lesions can be flexural or acral and can appear as macules, comedones, or cysts.
我们描述了一名具有类似重症氯痤疮临床特征的患者；然而，组织病理学检查结果显示为网状色素异常。该患者是一名机械师，有无数粉刺、许多囊肿、痤疮样瘢痕，以及屈侧和面部色素沉着。多氯联苯血清检测呈阴性，排除了氯痤疮的诊断。本文讨论了组织学明确的Dowling-Degos病的临床特征谱；在这种疾病中，皮损可发生于屈侧或肢端，可表现为斑疹、粉刺或囊肿。
