Pablo Méndez J, Carranza Lira S, Ulloa-Aguirre A, Pérez-Palacios G
Departamento de Biología de la Reproducción, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
Rev Invest Clin. 1992 Jan-Mar;44(1):103-8.
A new case of isosexual precocious puberty due to the presence of a subarachnoid cyst is reported. A female patient 16 months old was brought to our outpatient clinic because she had had two episodes of endometrial bleeding. Activity of the hypothalamic-pituitary-ovarian axis was demonstrated by pubertal concentrations of LH, FSH and estradiol. An arteriography and a CT demonstrated the presence of a subarachnoid cyst which was conditioning the pubertal process. Surgical resection of almost all the cyst, along with shunting, did not suppress endocrine activity. Suppressive treatment with medroxyprogesterone acetate was prescribed in order to accomplish the arrest of the pubertal process.
报告了一例因蛛网膜下囊肿导致的同性性早熟新病例。一名16个月大的女性患者因出现两次子宫内膜出血被带到我们的门诊。青春期水平的促黄体生成素(LH)、促卵泡生成素(FSH)和雌二醇表明下丘脑 - 垂体 - 卵巢轴功能活跃。动脉造影和计算机断层扫描(CT)显示存在一个正在引发青春期发育过程的蛛网膜下囊肿。几乎切除了整个囊肿并进行分流手术,但并未抑制内分泌活动。为了使青春期发育过程停止,开了醋酸甲羟孕酮抑制治疗的处方。