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[一名患艾滋病青少年的冠状动脉病变与心肌病相关]

[Coronary arteriopathy associated with cardiomyopathy in an adolescent with AIDS].

作者信息

Sadowinski-Pine S, Cabrera-Muñoz M L, Valencia-Mayoral P, Ramón-García G, Santos-Preciado J I

机构信息

Departamento de Patología Experimental y Clínica, Hospital Infantil de México Federico Gómez, México, D.F.

出版信息

Bol Med Hosp Infant Mex. 1992 Sep;49(9):605-9.

PMID:1388786
Abstract

The purpose of this paper is to inform the case of a 15 years old male patient who died as a consequence of acquired immunodeficiency syndrome (AIDS) complications. The postmortem examination showed a coronary lesion which, to the best of our knowledge, has not been previously described. This vasculopathy was restricted to the coronary arteries; myocardial changes similar to those described in AIDS-associated dilated cardiomyopathy were also present. The coronariopathy was indistinguishable from that described in the blood vessels of the brain in patients with AIDS-related cerebral arteriopathy. We also reviewed the autopsy material from another 14 children who died of AIDS, an in none of them exhibited similar changes in the coronary arteries. In addition we present the clinical findings and some theoretical considerations regarding the pathogenesis of the lesions.

摘要

本文旨在报告一例15岁男性患者因获得性免疫缺陷综合征(AIDS)并发症死亡的病例。尸检显示有一处冠状动脉病变,据我们所知,此前尚未有过相关描述。这种血管病变仅限于冠状动脉;同时还存在与AIDS相关扩张型心肌病中所描述的类似心肌变化。该冠状动脉病与AIDS相关脑动脉病患者大脑血管中所描述的病变难以区分。我们还回顾了另外14例死于AIDS的儿童的尸检材料,他们中没有一人的冠状动脉出现类似变化。此外,我们还介绍了临床发现以及关于病变发病机制的一些理论思考。

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